TINU syndrome and lymphoid interstitial alveolitis: a new observation

TINU syndrome is a rare entity known Dobrin disease, combining uveitis mostly bilateral and recurrent with acute tubulo interstitial nephritis [AIN] occurring in young adults. The etiology and pathogenesis of this syndrome remain unknown. Aim: To report a new case of TINU syndrome and to discuss its etiopathogenesis. This 33 year old women is hospitalized for exploration of acute renal failure, in a context of deterioration of general condition, associated with a unilateral anterior uveitis. The bronchoalveolar lavage showed lymphoid interstitial alveolitis with CD4 and the renal biopsy found lesions characteristic of AIN. Evolution under cortico'id treatment was favorable. Lymphoid interstitial alveolitis associated with TINU syndrome has been reported only twice before. The discovery of a TINU syndrome must practice bronchoalveolar lavage in search of sub clinical pulmonary involvement

[Fatal post transfusional hepatitis CMV of fatal outcome]

The cytomegalovirus [CMV] infection is most often asymptomatic, serious forms are confined to immunocompromised. We report a new case of post-transfusionnel hepatitis CMV of fatal outcome. A 83 year old man, asthmatic known for 26 years treated of corticosteroids, without particular hepatic antecedents, has presented an acute hepatitis post-.transfusionnel CMV of fatal outcome. The authors suggest widening the indications transfusion with the blood without leucocytes to the old persons fragile and/or whose immunizing status is precarious

[Ethical issues of new communication and information technologies applied in medicine]

The fast development of New Communication and Information Technologies [NTIC] and their use in increasingly numerous fields in medicine; raised new ethical issues. The aim of this paper is to highlight ethical and deontological guidelines for health professionals and physicians which must guide their use of the NTIC. A research in the Anglophone and French medical literature and on the Internet, using various key words related to ethics and medical computing. Ethical issues are mainly related to the property, the access and the use of the broad data bases of medical records, the legal obligations and ethics which must govern the course of a teleconsultation or a therapeutic remote intervention and the rules which must define the relationship between the teleconsultants and their patients. The use, increasingly frequent, of various expert systems of decision-making and/or of expertise in various clinical settings, also, poses ethical problems relating to the reliability of such systems, the qualifications necessary for their application and the responsibility for their development, maintenance and use. Medical information available on the Internet, of a very unequal and not controlled quality, raises many questions about the responsibility for the medical professionals in the education for the patients and their warning against sometimes erroneous information published on the Web. The ethical rules of research on the Internet must also be clearly formulated and diffused among the researchers. The general principles infront of an ethical problem related to the use of the NTIC remain based on the interest of the patient, the absence of a harmful effect, the respect of the professional secrecy and the safeguarding of the quality of the care and its conformity to the most recent scientific data